Complement C3c Antikörper

Produktnummer ABIN206657

Der Maus Monoklonal Anti-Complement C3c Antikörper wurde für ELISA, WB, IHC, FACS und IHC (fro) validiert. Er ist geeignet, Complement C3c in Proben von Human zu detektieren.

Kurzübersicht für Complement C3c Antikörper (ABIN206657)

Target: Complement C3c (C3C) (Complement Component C3c (C3C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Complement C3c Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Complement C3c Antikörper

Spezifität: Recognizes 135kD complement component 3c (C3c), present in blood serum. C3c is generated over the course of complement activation, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a. C3b is further degraded into iC3b and C3dg/C3d. iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha chain fragment 1 + alpha chain fragment 2), C3dg and C3f. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation. Binds both C3c and C3 and so is not suitable for all ELISA applications.

Aufreinigung: Protein A purified

Immunogen: Native human C3 from normal serum, highly purified by chromatography.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo, IHC, IHC-Fr, WB

Usage: ELISA: LS-C44974 binds both C3c and C3 and so is not suitable for all ELISA applications. Western Blot: LS-C44974 binds both C3c and C3 and so is not suitable for all ELISA applications.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Borate buffered saline, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. Store undiluted.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.

Details zu Complement C3c

Target: Complement C3c (C3C) (Complement Component C3c (C3C))

Andere Bezeichnung: Complement C3/C3c

UniProt: P01024